stem cell treatment - An Overview
With the concept that a far more quick cell cycle can be a essential element of pluripotency, reprogramming efficiency might be enhanced. Methods for enhancing pluripotency by way of manipulation of cell cycle regulators include: overexpression of Cyclin D/Cdk4, phosphorylation of Sox2 at S39 and S253, overexpression of Cyclin A and Cyclin E, knock